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typhoid vaccines, attenuation of immunization cannot be excluded. Low levels of an enzyme called Glucose-6-phosphate dehydrogenase (G6PD). Similarly, if previous prophylaxis with Mefloquine has failed, Mefloquine should not be used for curative treatment. The major metabolite, 3-hydroxyquinine, is less active than the parent drug. Qualaquin - Clinical Pharmacology Mechanism of Action Quinine is an antimalarial agent see Clinical Pharmacology (12.4). Therefore, drug-drug interactions could also occur with drugs that are substrates or are known to modify the expression of this transporter. There are insufficient clinical data to document the effect of Mefloquine in malaria caused.

Qualaquin - FDA prescribing information, side effects and uses



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Quinine has neuromuscular blocking activity, and may exacerbate muscle weakness. See USP Controlled Room Temperature Dispense in a tight container as defined in the USP. Therefore, if Qualaquin is co-administered to patients receiving theophylline or aminophylline, plasma theophylline concentrations should be monitored frequently to ensure therapeutic concentrations. Rifampin (CYP3A4 inducer In patients with uncomplicated. Neuropsychiatric: headache, diplopia, confusion, altered mental status, seizures, coma, disorientation, tremors, restlessness, ataxia, acute dystonic reaction, aphasia, and suicide. What should I avoid while taking mefloquine? Drug Interactions Effects of Drugs and Other Substances on Quinine Pharmacokinetics Quinine is a P-gp substrate and is primarily metabolized by CYP3A4. Qualaquin oral capsules are not approved for: Treatment of severe or complicated.

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